Glossary

Adipose tissue is the fatty tissue in the body. It is a loose connective tissue composed mostly of fat cells. In addition, adipose tissue contains many other functional cells, and is a convenient source of a number of cell types potentially useful in therapy. This includes the population which is the source of mesenchymal stromal cells used in MedXCell products.

Allogeneic (cell therapy) refers to cells harvested from one individual (donor) and used for therapy after modification or at a later date in one or more different individuals (recipients).
Autologous (cell therapy) refers to cells harvested from one individual and used for therapy after modification or at a later data on the same individual (donor and recipient are the same individual).

MSC’s are a population of cells which can be isolated from human tissue such as bone marrow and adipose tissue based on definitive characteristics. These populations of cells have important functional capabilities such as immune modulation, inflammation modulation and tissue repair through their cell signalling abilities and ability to self-transform into a number of differentiated cell types upon appropriate stimulation. Such abilities are exploited in cell therapy when MSC’s are injected into a site of injury or disease.

Osteoarthritis is the most common form of arthritis, affecting millions of people worldwide. It occurs when the protective cartilage that cushions the ends of bones wears down over time or from trauma. Although osteoarthritis can damage any joint, the disorder most commonly affects joints in the hands, knees, hips and spine.
Regenerative medicine is a therapeutic strategy which deals with the process of replacing, repairing or regenerating human or animal cells, tissues or organs to restore or establish normal function. This field includes both repairing damaged tissues and organs by stimulating the body’s own repair mechanisms to functionally heal previously damaged tissues or organs as well as the formation of new tissue outside the body for eventual transplantation.